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In early January 2023, the Journal of Sexual Medicine published a study showing that men who regularly take erectile dysfunction drugs belonging to the category of PDE-5 inhibitors, in particular Cialis, are 25% less likely than the control group to suffer premature death. They are also less likely to experience heart problems.

The study involved almost 24,000 men who took drugs from the group of PDE-5 inhibitors between 2006 and 2020. The control group consisted of twice as many men. Only those men who received medications in accordance with the insurance plan were considered. In addition to such a criterion as obtaining a prescription for tadalafil or another PDE-5 inhibitor, the researchers paid attention to the medical expenses of patients, such as hospitalizations, various medical procedures, drugs, clinic visits, as a result of which they could obtain fairly objective information about the health status of the study subjects. During the study, a research team from the Huntington Medical Research Institute in Pasadena, California, used data from the National Death Index. NDI is a federal database of all deaths reported in the United States.

The data from this study confirmed that men taking PDE-5 inhibitors, especially those taking Tadalafil, were almost 15% less likely to experience severe cardiovascular complications, including heart failure, coronary revascularization, unstable angina, and almost 40% less death rate due to cardiovascular disease. Of course, the focus of attention of the researchers were mainly men over the age of 55 years. The absolute reliability of this study has not yet been proven, however, many patients taking PDE-5 inhibitors on a regular basis noted that their well-being in terms of the state of the cardiovascular system improved, despite the fact that heart disease is one of the contraindications to taking these geneirc Cialis The PDE-5 enzyme is produced in smooth muscle, which is part of the walls of blood vessels throughout the body. Therefore, after taking Tadalafil and other PDE-5 inhibitors, the blood vessels expand and fill with blood, which contributes to the onset of an erection, and also increases the amount of blood that passes through the coronary arteries to the heart, and reduces the stiffness of the arteries in general. Thanks to this, the heart doesn’t have to work as hard as before to pump blood throughout the body.

Tadalafil is used to treat not only ED, but also conditions such as pulmonary hypertension, when it is necessary to dilate blood vessels and provide blood flow to areas that have nothing to do with the genitals. So, Tadalafil is used even in children with some congenital heart defects.

Of course, the use of Cialis solely for the purpose of improving the state of the cardiovascular system is unreasonable. However, if you don’t have strict contraindications to taking Tadalafil, such as decompensated heart failure, the use of this medicine will help you not only restore your potency, but also improve the condition of the cardiovascular system. Most older men take Cialis because it is the only PDE-5 inhibitor that can be used for prostate adenoma. Therapy is practiced on a daily basis. In this regard, Cialis generics are becoming increasingly popular, as they are much more affordable for a wide range of patients.